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  • Simmons ST, Basic and Clinical Science Course: Section 10: Glaucoma, San Francisco, California: American Academy of Ophthalmology; 2005.
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    Although the exact cause of primary openangle glaucoma is not known, it seems to be related to increased resistance to outflow of aqueous through the trabecular meshwork. This progressive resistance to outflow results in a gradual increase in intraocular pressure, which may result in glaucomatous optic nerve damage in susceptible patients.